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Cat. No. | Product Name | Target | Signaling Pathways |
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T37943 |
17-phenyl trinor Prostaglandin F2α isopropyl ester
17-phenyl trinor Prostaglandin F2α isopropyl ester |
Others | Others |
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP r... | |||
T37946 |
17-trifluoromethylphenyl trinor Prostaglandin F2α
17-trifluoromethylphenyl trinor Prostaglandin F2α |
Others | Others |
A number of 17-phenyl trinor prostaglandin F2α (17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma. Of these, the unsubstituted or meta-substituted aromatic derivatives are the most potent FP receptor agonists. 17-trifluoromethylphenyl trinor PGF2α bears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As an ocular hypotensive agent, it would be expected that 17-trifluoromethylphenyl trin... | |||
T37948 |
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α
17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α |
Others | Others |
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relatively good potency, but show a significantly reduced incidence of local irritant side effects.417-trifluoromethylphenyl-13,14-dihydro trinor PGF2αbears an aromatic ring which is reminiscent of the trifluoromethyl-phenoxy ring of travoprost ((+)-fluprostenol isopropyl ester). As a... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00423 |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc)
BFR-1,KGFR,TK25,JWS,ECT1,K-SAM,FGFR2 α(IIIb),CD332,fibroblas... |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (alpha IIIb, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66.3 kDa and the accession number is P21802-17. |