Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39074 |
(Rac)-Zevaquenabant
(Rac)-MRI-1867,(Rac)-Zevaquenabant |
Others | Others |
(Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a potent and selective antagonist of the cannabinoid receptor type 1 (CB1R) and inducible nitric oxide synthase (iNOS), exhibiting a binding affinity (Ki) of 5.7 nM specifically for CB1R. Due to its characteristics, (Rac)-Zevaquenabant holds promise as an investigative tool in liver fibrosis research. | |||
T39410 |
Zevaquenabant
(S)-MRI-1867 |
Others | Others |
Zevaquenabant ((S)-MRI-1867), a dual cannabinoid CB1 receptor and inducible NOS (iNOS) antagonist, is orally bioavailable and peripherally restricted. It effectively mitigates obesity-induced chronic kidney disease (CKD). |