Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10046 |
16,16-Dimethyl prostaglandin E2
16,16-dimethyl PGE2 |
Prostaglandin Receptor | GPCR/G Protein; Immunology/Inflammation |
16,16-Dimethyl prostaglandin E2 is an orally active vertebrate Hematopoietic stem cells homeostasis critical regulator. It can act through EP2/EP4 and has an interaction with the Wnt pathway. | |||
T36829 |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 |
Others | Others |
9-deoxy-9-methylene-16,16-dimethyl Prostaglandin E2 (Meteneprost) is a potent analog of prostaglandin E2 with an extended half-life in vivo. In combination with various other prostaglandin derivatives, it results in the termination of first trimester pregnancy in monkeys. A single intramuscular injection containing 0.5 mg of meteneprost and 7.5 mg of 17-phenyl trinor PGF1α is very effective in terminating early pregnancy. This prostaglandin mixture is ineffective on monkeys in their third trimes... | |||
T84585 |
11-deoxy-16,16-dimethyl Prostaglandin E2
11-deoxy-16,16-dimethyl PGE2 |
Others | Others |
11-Deoxy-16,16-dimethyl Prostaglandin E2 (11-deoxy-16,16-dimethyl PGE2) is a stable synthetic analog of Prostaglandin E2 (PGE2), acting as an agonist for both EP2 and EP3 receptors. It effectively inhibits gastric acid secretion and ulcer formation in rats, with ED50 values of 1 mg/kg and 0.021 mg/kg, respectively. This compound is also 900 times more potent than Prostaglandin F2α (PGF2α) in inducing contraction of human respiratory tract smooth muscle in vitro. |