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Search Results for " 15(r) lipoxin a4 "
Targets Recommended: Others

3

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T37265 15(R)-Lipoxin A4

15(R)-Lipoxin A4,AT-Lipoxin A4

Others Others
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function. 15(R)-Lipoxin A4 (15(R)-LXA4) is derived from the aspirin-triggered formation of 15(R)-HETE from arachidonic acid. [1] [2] 15(R)-LXA4 inhibits LTB4-induced chemotaxis, adherence, and transmigration of neutrophils with twice the potency of LXA4 demonstrating activity in the nM range.[2] [3] The anti-inflammatory effects of aspirin may...
T84605 15(R)-HETE

15(R)-Hydroxyeicosatetraenoic Acid

Others Others
15(R)-HETE, a monohydroxy fatty acid, is synthesized from arachidonic acid via aspirin-acetylated COX-2, leading to the formation of specialized pro-resolving mediators 15(R)-lipoxin A4 and B4 through a transcellular mechanism involving 5-lipoxygenase (5-LO). Additionally, this compound is produced by the cytochrome P450 (CYP) isoform CYP2C9 and can be generated from arachidonic acid by COX-1 in human mast cells, where it accumulates due to its resistance to conversion into 15-KETE by 15-hydroxy...
T37305 6(S)-Lipoxin A4

6(S)-Lipoxin A4

Others Others
The lipoxins are trihydroxy fatty acids containing a 7,9,11,13-conjugated tetraene. Lipoxin A4 (LXA4) was first described as a metabolite of 15-HpETE and/or 15-HETE when added in vitro to isolated human leukocytes. The material obtained in this manner consists of at least four distinct isomers: 5(S), 6(S); 5(S), 6(R); and the 11-trans and 11-cis isomers of each of these. 6(S)-LXA4 is one of the original four metabolites first identified by Serhan, Nicolaou, and Samuelsson. It was considered to b...

化合物

15(R)-Lipoxin A4
Cat.No: T37265
Synonym: 15(R)-Lipoxin A4,AT-Lipoxin A4
Target: Others
15(R)-HETE
Cat.No: T84605
Synonym: 15(R)-Hydroxyeicosatetraenoic Acid
Target: Others
6(S)-Lipoxin A4
Cat.No: T37305
Synonym: 6(S)-Lipoxin A4
Target: Others
Cat. No. Product Name Species Expression System
TMPY-00803 Fibronectin Protein, Human, Recombinant (aa 607-1265, His)

GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,...

Human HEK293 Cells
Fibronectin Protein, Human, Recombinant (aa 607-1265, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.2 kDa and the accession number is P02751-15.
TMPY-05562 Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)

fibronectin 1,ED-B,CIG,FNZ,MSF,FN,FINC,GFND,LETS,GF...

Human HEK293 Cells
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa and the accession number is P02751-15.
TMPK-01416 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated

MHC,SARS-CoV-2 epitope

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.
TMPK-01412 HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)

SARS-CoV-2 epitope,MHC

Human HEK293 Cells
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype.

重组蛋白

Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
Cat.No: TMPY-00803
Species: Human
Expression System: HEK293 Cells
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)
Cat.No: TMPY-05562
Species: Human
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
Cat.No: TMPK-01416
Species: Human
Expression System: HEK293 Cells
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
Cat.No: TMPK-01412
Species: Human
Expression System: HEK293 Cells
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