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Cat. No. Product Name Target Signaling Pathways
T84963 5α-Androstan-3β-ol

NSC 50887

Others Others
5α-Androstan-3β-ol, a steroidal androgen, demonstrates selective interaction with cellular components, showing affinity for the androgen receptor (AR) with an IC50 of 1.7 µM and activating the pregnane X receptor (PXR) in HepG2 cells with an EC50 of 0.8 µM. It selectively inhibits the hydroxylase activities of 16α- and 6β-hydroxylase over 16β- or 7α-hydroxylase, with IC50 values of 70 and 110 µM, compared to >150 µM for the latter enzymes, indicating a specificity in its enzyme inhibition profil...

化合物

5α-Androstan-3β-ol
Cat.No: T84963
Synonym: NSC 50887
Target: Others
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