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Search Results for " α1a "

Targets Recommended: PROTACs

60

抑制剂 & 化合物

3

天然产物

5

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T74557	α1A-AR Degrader 9c	PROTACs	PROTAC
	α1A-AR Degrader 9c（化合物 9c）是一种高效、选择性且可逆的α1A-AR PROTAC降解剂，DC50值为2.86 μM。它通过蛋白酶体途径诱导α1A-AR的降解，并且在抑制PC-3细胞增殖方面表现出活性，IC50为6.12 μM。此外，α1A-AR Degrader 9c展现出在前列腺癌研究中的抗肿瘤潜力。
T41231	GP 1a	Cannabinoid Receptor; PERK; Arrestin	Apoptosis; GPCR/G Protein
	GP 1a 是cannabinoid receptor 2（CB2）的强效激动剂（EC50=7.1),是在cAMP、GTPγS 和β-arrestin 招募试验中显示的。GP 1a 对CB2受体的选择性约为CB1受体的30倍，且在体外增加HL-60细胞的P-ERK1/2表达。GP 1a 对皮肤伤口愈合有益。GP 1a 可抑制炎症和纤维生成，同时促进上皮的重新形成。
T1132	Nicergoline 尼麦角林,Nicergolinum,Nimergoline	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Nicergoline (Nicergolinum) 是一种有效的，选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂，是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用，可以改善阿尔茨海默症小鼠的认知功能。
T38160	STING Agonist 1a	Others	Others
	STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir...
T76469	Esculentin 1A
	Esculentin 1A 是一种青蛙皮肤来源的抗菌肽(AMP)，具有强大的体外抗假单胞菌活性。
T30873	Chelator 1a Chelator1a,Chelator-1a	Antifungal	Microbiology/Virology
	Chelator 1a 具有抗真菌活性，抑制曲霉菌和念珠菌，可用于研究真菌感染和癌症。
T63873	Anti-Aβ agent 1A	Others	Others
	Anti-Aβ agent 1A 是有效的抗淀粉样蛋白-β (amyloid-β) 剂。Anti-Aβ agent 1A 可明显抑制 LPS 诱导的 IL-1β、IL-6 和 TNF-α 水平，并能够利用线粒体途径减少 H2O2诱导的 SH-SY5Y 细胞凋亡，表现出抗氧化、抗炎、抗 Aβ 毒性和神经保护活性。Anti-Aβ agent 1A 能够用于研究阿尔兹海默症。
T83857	Soluble Epoxide Hydrolase PROTAC 1a sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a	Others	Others
	Soluble epoxide hydrolase (sEH) PROTAC 1a是一种利用蛋白质降解靶向嵌合体(PROTAC)技术，通过连接区域将cereblon配体1与sEH抑制剂t-TUCB结合。该化合物通过促进sEH的降解，特异性抑制sEH的水解酶活性(IC50 = 0.8 nM)，相较于其磷酸酶活性(IC50 = >10,000 nM)具有较高选择性。sEH PROTAC 1a还特定促进细胞质中而非过氧体中的sEH降解，并通过溶酶体而非蛋白酶体实现其降解。它能够降低thapsigargin诱导的HepG2与293T细胞中磷酸化的inositol-requiring enzyme 1α (IRE1α)水平和X-box结合蛋白1 (XBP1)剪接，表明能减少ER应激。
T36219	1a,1b-dihomo Prostaglandin E1 1a,1b-dihomo Prostaglandin E1	Others	Others
	1a,1b-dihomo Prostaglandin E1 是一类前列腺素化合物。
T36045	1a,1b-dihomo Prostaglandin E2 1a,1b-dihomo Prostaglandin E2	Others	Others
	1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid . 1a,1b-dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid . This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.
T84573	1a,1b-dihomo Prostaglandin F2α 1a,1b-dihomo PGF2α	Others	Others
	1a,1b-Dihomo Prostaglandin F2α (1a,1b-dihomo PGF2α), a hypothetical product of adrenic acid in the COX pathway, is predominantly synthesized in the renal medulla, reflecting the selective distribution of adrenic acid in this region.
T131451	Methyl 1a,7a,14a-triacetoxy-8,15-isopimaredien-18-oate	Others	Others
	Methyl 1a,7a,14a-triacetoxy-8,15-isopimaredien-18-oate 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131451。
T16798	RS 17053 hydrochloride RS-17053	Others; Adrenergic Receptor	GPCR/G Protein; Neuroscience; Others
	RS 17053 hydrochloride 是有效的、选择性的 α1A 肾上腺素受体 (α1A adrenoceptor) 拮抗剂。RS 17053 hydrochloride 在细胞膜中测得的 pKi 值为 9.1，功能分析的 pA2 值为 9.8。
T12643	(R)-Terazosin (R)-特拉唑嗪,盐酸特拉唑嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(R)-Terazosin 是一种 Terazosin 的活性 R 型对映体, 是 α1-肾上腺素受体拮抗剂，对 α1a，α1b 和α1d-肾上腺素受体的Ki 分别为 6.51 nM，1.01 nM 和 1.97 nM。
T23301	(S)-(+)-Niguldipine hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(S)-(+)-Niguldipine hydrochloride 是一种选择性 α1A-AR 拮抗剂，可用于研究抑郁症和癫痫。
T23253	RS 100329 hydrochloride RS-100329	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	RS 100329 hydrochloride 是α1A 肾上腺素能受体的拮抗剂。
T9762	Upidosin SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Upidosin (SB-216469) 是一种有效的、选择性的α1-肾上腺素受体拮抗剂，α1a 亚型Ki=0.34nM，α1b 亚型Ki=3.9nM，β1d 亚型Ki=1.5nM，γ2-肾上腺素受体Ki=33.3nM。
T13110	Tedatioxetine hydrobromide Lu AA 24530 hydrobromide	Dopamine Receptor; 5-HT Receptor; Norepinephrine	GPCR/G Protein; Neuroscience
	Tedatioxetine hydrobromide (Lu AA 24530 hydrobromide) 是一种血清素-去甲肾上腺素-多巴胺再摄取抑制剂，也是 5-HT2A、5-HT2C、5-HT3 和 α1A-肾上腺素能受体的拮抗剂，可用于治疗抑郁症和焦虑症。
T9220	Naftopidil hydrochloride 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil hydrochloride (BM-15275 hydrochloride) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力 Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T1504	Silodosin 西洛多辛,KAD 3213,KMD 3213	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Silodosin (KAD 3213) 是有选择性的、强效的、口服活性的 α1A-adrenergic receptor 阻滞剂，是一种有效且耐受性良好的试剂，可用于研究 LUTS/BPH。它对 α1A-AR 表现出高度的亲和力，是 α1B-AR 和 α1D-AR 亲和力的 162 和 50 倍。
T63980	BODIPY FL prazosin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	BODIPY FL prazosin 是一种高效的 α1-肾上腺素拮抗剂，抑制 α1a-AR 和 α1b-AR. BODIPY FL prazosin 是一种荧光配体（λEx(nm)/ λEm (nm)： 485/535），常与流式细胞术或共聚焦激光扫描显微镜一起研究α1-肾上腺素亚型和细胞成像。
T1090	Perphenazine Perphenazin,Etaperazine,Trilafon,奋乃静	CaMK; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Perphenazine (Trilafon) 是吩噻嗪衍生物和多巴胺拮抗剂，具有止吐和抗精神病特性。它能够抑制5-HT2A 受体，α1A 肾上腺素能受体，多巴胺D2、D3、D2L 受体，以及组胺H1受体，对应的Ki 值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
T0696	Naftopidil KT-611,萘哌地尔,BM-15275	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil (KT-611) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM 、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T6600	Naftopidil dihydrochloride KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil dihydrochloride (KT-611 2HCl) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T3046	BMY 7378 dihydrochloride BMY7378 HCl	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	BMY 7378 dihydrochloride (BMY7378 HCl) 是选择性 α1D 肾上腺素受体拮抗剂，也是5-HT1A 受体部分激动剂。它同表达克隆大鼠 α1D-AR 的膜结合的亲和力 (Ki=2 nM) 是同克隆大鼠 α1A-AR (Ki=800 nM) 或仓鼠 α1B-AR (Ki=600 nM) 结合的亲和力的100 以上。
T27401	Garomefrine HCl PNO-49B,NS-49,ABT-232,ABT232,NS49,PNO49B	Others	Others
	Garomefrine HCl, a α1A-adrenoceptor agonist, is potential for the treatment of urinary incontinence.
T10523	β3-AR agonist 1	Others	Others
	β3-AR agonist 1 is a highly selective, and orally available agonist of β3-adrenergic receptor (EC50: 18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold).
T14972	Cirazoline hydrochloride LD 3098 hydrochloride	Others	Others
	Cirazoline hydrochloride is a competitive full agonist of the α1A-adrenergic receptor (α1A-AR; Ki: 120 nM). It is a partial agonist at α1B-AR (Ki: 960 nM) and α1D-AR (Ki: 660 nM).
T24378	L-771688 dihydrochloride L 771688 dihydrochloride	Others	Others
	L-771688 is an α1A-adrenoceptor antagonist potentially for the treatment of benign prostatic hyperplasia.
T85248	Phenylephrine Glucuronide	Others	Others
	Phenylephrine glucuronide, a metabolite of phenylephrine (an α1A-adrenergic receptor agonist), is produced through metabolic processes.
T23374	SNAP 5089	Others	Others
	α1A-adrenoceptor antagonist
T23532	WB 4101 hydrochloride	Others	Others
	α1A-adrenergic antagonist
T82072	Indoramin hydrochloride Indoramine hydrochloride,Wy 21901 hydrochloride	Others	Others
	Indoramin (hydrochloride) is a novel antihypertensive agent that exhibits selectivity for the α1A-adrenergic receptor.
T28617	RS 100329 RS100329 HCl,RS 100329 HCl,RS100329,RS-100329	Others	Others
	RS 100329 HCl is a selective α1A-adrenoceptor antagonist (pKi = 9.6 for human cloned α1A receptors).
T80477	Muscarinic toxin 3 MT3	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Muscarinic toxin 3 (MT3) 是高效的非竞争性mAChR及adrenoceptors拮抗剂，对M1、M4、α1A、α1B、α1D、α2A、α2B、α2C受体展示出不同程度的选择性，其pIC50值分别为6.71、8.79、8.86、7.57、8.13、8.49、6.5、7.29。该化合物具有显著的肾上腺素受体抑制活性。
T80505	PKCα (C2-4) inhibitor peptide	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	PKCα(C2-4) inhibitor peptide为专一性PKCα抑制剂，能够抑制α1A‐肾上腺素受体激动剂A-61603对IKr通道的影响。
T23225	(R)-(-)-Niguldipine hydrochloride	Others	Others
	(R)-(-)-Niguldipine hydrochloride is a L-type Ca2+ channel blocker and α1A-adrenoceptor antagonist.
T71335	PF-3774076	Others	Others
	PF-3774076 is a CNS penetrant, potent, selective, partial agonist at the human α1A adrenoceptor. PF-3774076 is selective over α1B and α1D adrenoceptors.
T35576	Phenylephrine-3-O-Sulfate	Others	Others
	Phenylephrine-3-O-sulfate is metabolite of the α1A-adrenergic receptor agonist phenylephrine formed via sulfation.
T12815	(S)-Terazosin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity antagonist of α-adrenoceptor(α1a, α1b and α1d-adrenoceptor with Ki values of 3.91 nM, 0.79 nM and 1.16 nM, respectively).
T15688	L-771688 SNAP 6383	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-771688（SNAP 6383）是一种新型有效和选择性的 α1A-肾上腺素受体拮抗剂， Ki 值为 0.43±0.02 nM。L-771688 KE 用于治疗良性前列腺增生。
T36071	Silodosin Glucuronide (sodium salt)	Others	Others
	Silodosin glucuronide is an active metabolite of the α1A-adrenergic receptor antagonist silodosin . It is formed from silodosin by the UDP-glucuronosyltransferase (UGT) isoform UGT2B7. Silodosin glucuronide is toxic to rats with an LD50 value of 0.347 mg/kg.
T11286	Fiduxosin A 185980.1,ABT 980	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fiduxosin 是一种具有选择性和有效性的 α1-adrenoceptor 拮抗剂，对 α1a-adrenoceptor，α1b-adrenoceptor 和 α1d-adrenoceptor 有抑制作用，Ki 值分别为 0.160 nM，24.9 nM 和 0.920 nM。Fiduxosin 可用于治疗良性前列腺增生。
T5384	RS 504393	CCR	Immunology/Inflammation; Microbiology/Virology
	RS 504393 是一种高度选择性的 CCR2 趋化因子受体拮抗剂，作用于人重组 CCR2 和 CCR1 受体，IC50值分别为 89 nM 和大于 100 μM。
T73447	NP10679	P450; HER; NMDAR; Histamine Receptor	Angiogenesis; GPCR/G Protein; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Neuroscience; Tyrosine Kinase/Adaptors
	NP10679 是一种可口服且具有选择性、脑穿透性、高效性和 pH 敏感性的 GluN2B 亚基的 N-methyl-D-aspartate (NMDA) 受体抑制剂。NP10679 抑制 histamine H1 、 hERG 通道和 CYP 酶，可用于研究癫痫和缺血性卒中。
T64314	OxyMetazoline	Others	Others
	OxyMetazoline 是一种 α-肾上腺素受体 (α-adrenoceptor) 激动剂，能够作用于 α1A (IC50: 0.02 μM)、α1B (IC50: 0.25 μM)、α2A (IC50: 0.58 μM) 和 α2C (IC50: 0.13 μM)。OxyMetazoline 能够用于研究缓解鼻黏膜充血。
TP2086	AdTx1
	Selective, high affinity, non-competitive α1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including α2A, β1 and β2 adrenoceptors. Antagonizes effects of phenylephrine on isolated rabbit prostate
T80175	Conopeptide rho-TIA	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Conopeptide rho-TIA为从掠食性海螺Conus tulipa毒液中提炼的多肽，对人类α1B-Adrenergic Receptor呈现非竞争性抑制作用，同时对α1A-Adrenergic Receptor和α1D-Adrenergic Receptor表现出竞争性抑制。Conopeptide rho-TIA与这些亚型的结合特性可能对开发针对α1-Adrenergic Receptor亚型的选择性新药具有参考价值。
TQ0283	RS102895	CCR	Immunology/Inflammation; Microbiology/Virology
	RS102895 是一种CCR2拮抗剂，IC50值为 360 nM。
T69031	Cirazoline (free base)	Others	Others
	Cirazoline (free base) is a full agonist at the α1A adrenergic receptor, a partial agonist at both the α1B and α1D adrenergic receptors, and a nonselective antagonist to the α₂ adrenergic receptor. It is believed that this combination of properties could make cirazoline an effective vasoconstricting agent.

化合物

α1A-AR Degrader 9c

Cat.No: T74557

Target: PROTACs

Cat.No: T41231

Target: Cannabinoid Receptor, PERK, Arrestin

Cat.No: T1132

Synonym: 尼麦角林,Nicergolinum,Nimergoline

Target: Adrenergic Receptor

STING Agonist 1a

Cat.No: T38160

Target: Others

Cat.No: T76469

Cat.No: T30873

Synonym: Chelator1a,Chelator-1a

Target: Antifungal

Anti-Aβ agent 1A

Cat.No: T63873

Target: Others

Soluble Epoxide Hydrolase PROTAC 1a

Cat.No: T83857

Synonym: sEH Proteolysis-targeting Chimera 1a,Soluble Epoxide Hydrolase Proteolysis-targeting Chimera 1a,sEH PROTAC 1a

Target: Others

1a,1b-dihomo Prostaglandin E1

Cat.No: T36219

Synonym: 1a,1b-dihomo Prostaglandin E1

Target: Others

1a,1b-dihomo Prostaglandin E2

Cat.No: T36045

Synonym: 1a,1b-dihomo Prostaglandin E2

Target: Others

1a,1b-dihomo Prostaglandin F2α

Cat.No: T84573

Synonym: 1a,1b-dihomo PGF2α

Target: Others

Methyl 1a,7a,14a-triacetoxy-8,15-isopimaredien-18-oate

Cat.No: T131451

Target: Others

RS 17053 hydrochloride

Cat.No: T16798

Synonym: RS-17053

Target: Others, Adrenergic Receptor

Cat.No: T12643

Synonym: (R)-特拉唑嗪,盐酸特拉唑嗪

Target: Adrenergic Receptor

(S)-(+)-Niguldipine hydrochloride

Cat.No: T23301

Target: Adrenergic Receptor

RS 100329 hydrochloride

Cat.No: T23253

Synonym: RS-100329

Target: Adrenergic Receptor

Cat.No: T9762

Synonym: SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739

Target: Adrenergic Receptor

Tedatioxetine hydrobromide

Cat.No: T13110

Synonym: Lu AA 24530 hydrobromide

Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine

Naftopidil hydrochloride

Cat.No: T9220

Synonym: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride

Target: Adrenergic Receptor

Cat.No: T1504

Synonym: 西洛多辛,KAD 3213,KMD 3213

Target: Adrenergic Receptor

BODIPY FL prazosin

Cat.No: T63980

Target: Adrenergic Receptor

Cat.No: T1090

Synonym: Perphenazin,Etaperazine,Trilafon,奋乃静

Target: CaMK, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Cat.No: T0696

Synonym: KT-611,萘哌地尔,BM-15275

Target: Adrenergic Receptor

Naftopidil dihydrochloride

Cat.No: T6600

Synonym: KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl

Target: 5-HT Receptor, Adrenergic Receptor

BMY 7378 dihydrochloride

Cat.No: T3046

Synonym: BMY7378 HCl

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Garomefrine HCl

Cat.No: T27401

Synonym: PNO-49B,NS-49,ABT-232,ABT232,NS49,PNO49B

Target: Others

β3-AR agonist 1

Cat.No: T10523

Target: Others

Cirazoline hydrochloride

Cat.No: T14972

Synonym: LD 3098 hydrochloride

Target: Others

L-771688 dihydrochloride

Cat.No: T24378

Synonym: L 771688 dihydrochloride

Target: Others

Phenylephrine Glucuronide

Cat.No: T85248

Target: Others

Cat.No: T23374

Target: Others

WB 4101 hydrochloride

Cat.No: T23532

Target: Others

Indoramin hydrochloride

Cat.No: T82072

Synonym: Indoramine hydrochloride,Wy 21901 hydrochloride

Target: Others

Cat.No: T28617

Synonym: RS100329 HCl,RS 100329 HCl,RS100329,RS-100329

Target: Others

Muscarinic toxin 3

Cat.No: T80477

Synonym: MT3

Target: Adrenergic Receptor

PKCα (C2-4) inhibitor peptide

Cat.No: T80505

Target: PKC

(R)-(-)-Niguldipine hydrochloride

Cat.No: T23225

Target: Others

Cat.No: T71335

Target: Others

Phenylephrine-3-O-Sulfate

Cat.No: T35576

Target: Others

Cat.No: T12815

Target: Adrenergic Receptor

Cat.No: T15688

Synonym: SNAP 6383

Target: Adrenergic Receptor

Silodosin Glucuronide (sodium salt)

Cat.No: T36071

Target: Others

Cat.No: T11286

Synonym: A 185980.1,ABT 980

Target: Adrenergic Receptor

Cat.No: T5384

Target: CCR

Cat.No: T73447

Target: P450, HER, NMDAR, Histamine Receptor

Cat.No: T64314

Target: Others

Cat.No: TP2086

Conopeptide rho-TIA

Cat.No: T80175

Target: Adrenergic Receptor

Cat.No: TQ0283

Target: CCR

Cirazoline (free base)

Cat.No: T69031

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
TN4117	GB 1a	Antioxidant; Tyrosinase	oxidation-reduction; Proteases/Proteasome
	GB 1a 是一种从藤黄 Garcinia travancorica 叶中分离出来的天然产物。
T17310	Phenylephrine 去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Phenylephrine ((R)-(-)-Phenylephrine) 是一种选择性的α1-肾上腺素受体激动剂，常用作减充血剂。
T0453	Phenylephrine hydrochloride NCI-c55641,Phenylephrine HCl,盐酸去氧肾上腺素,(R)-(-)-Phenylephrine hydrochloride	Endogenous Metabolite; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Phenylephrine hydrochloride (NCI-c55641) 是选择性的α1-肾上腺素能受体激动剂，对α1A，α1B 和α1D 受体的pKis 分为4.70，4.87和5.86。

天然产物

Cat.No: TN4117

Target: Antioxidant, Tyrosinase

Cat.No: T17310

Synonym: 去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine

Target: Adrenergic Receptor

Phenylephrine hydrochloride

Cat.No: T0453

Synonym: NCI-c55641,Phenylephrine HCl,盐酸去氧肾上腺素,(R)-(-)-Phenylephrine hydrochloride

Target: Endogenous Metabolite, Adrenergic Receptor

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00411	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	Baculovirus Insect Cells
	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.6 kDa and the accession number is Q195D4.
TMPH-02036	Human rhinovirus 1A (HRV-1A) Genome polyprotein (His) Genome polyprotein	HRV-1A	P. pastoris (Yeast)
	Human rhinovirus 1A (HRV-1A) Genome polyprotein (His) is expressed in Yeast.
TMPH-00349	Car b 1 isoforms 1A and 1B Protein, Carpinus betulus, Recombinant (His) Allergen Car b I,Major pollen allergen Car b 1 isoforms 1A a...	Carpinus betulus	E. coli
	Car b 1 isoforms 1A and 1B Protein, Carpinus betulus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.3 kDa and the accession number is P38949.
TMPY-00512	Influenza A H7N7 (A/equine/Kentucky/1a/1975) Hemagglutinin/HA Protein (His) Harvey rat sarcoma viral oncogene homolog	H7N7	Baculovirus Insect Cells
	Influenza A H7N7 (A/equine/Kentucky/1a/1975) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 61.6 kDa and the accession number is B8K0J1.
TMPY-03229	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His) Harvey rat sarcoma viral oncogene homolog	H5N1	HEK293 Cells
	Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.3 kDa and the accession number is Q195D4.

重组蛋白

Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00411

Species: H5N1

Expression System: Baculovirus Insect Cells

Human rhinovirus 1A (HRV-1A) Genome polyprotein (His)

Cat.No: TMPH-02036

Species: HRV-1A

Expression System: P. pastoris (Yeast)

Car b 1 isoforms 1A and 1B Protein, Carpinus betulus, Recombinant (His)

Cat.No: TMPH-00349

Species: Carpinus betulus

Expression System: E. coli

Influenza A H7N7 (A/equine/Kentucky/1a/1975) Hemagglutinin/HA Protein (His)

Cat.No: TMPY-00512

Species: H7N7

Expression System: Baculovirus Insect Cells

Influenza A H5N1 (A/bar-headed goose/Qinghai/1A/2005) Hemagglutinin/HA1 Protein (His)

Cat.No: TMPY-03229

Species: H5N1

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0206	(R)-(-)-Phenylephrine-2,4,6-d3
	(R)-(-)-Phenylephrine-2,4,6-d3 是 (R)-(-)-Phenylephrine 的氘代化合物。(R)-(-)-Phenylephrine 的 CAS 号为 59-42-7。Phenylephrine 是一种选择性的α1-肾上腺素受体激动剂，常用作减充血剂。
TMIJ-0004	Perphenazine-d4
	Perphenazine-d4 是 Perphenazine 的氘代化合物。Perphenazine 的 CAS 号为 58-39-9。Perphenazine 是吩噻嗪衍生物和多巴胺拮抗剂，具有止吐和抗精神病特性。它能够抑制5-HT2A受体，α1A肾上腺素能受体，多巴胺D2、D3、D2L受体，以及组胺H1受体，对应的Ki值分别为5.6、10、0.765、0.13、3.4 和 8 nM。
TMIJ-0251	Nicergoline-13C-d3
	Nicergoline-13C-d3 是 Nicergoline 的 13C 和氘代化合物。Nicergoline 的 CAS 号为 27848-84-6。Nicergoline 是一种有效的，选择性的、具有口服活性的α1A-肾上腺素能受体拮抗剂，是一种溴烟碱酸的麦角林衍生物。它具有血管舒张作用，可以改善阿尔茨海默症小鼠的认知功能。

同位素标记化合物

(R)-(-)-Phenylephrine-2,4,6-d3

Cat.No: TMIJ-0206

Perphenazine-d4

Cat.No: TMIJ-0004

Nicergoline-13C-d3

Cat.No: TMIJ-0251

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