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Search Results for " α1-adrenoceptor "

Targets Recommended: Others

40

抑制剂 & 化合物

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天然产物

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同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T10003	α1 adrenoceptor-MO-1	Others	Others
	α1 adrenoceptor-MO-1（S 对映体）对α1肾上腺素受体具有亲和力，具有抗α-肾上腺素能和镇痛作用。α1 adrenoceptor-MO-1比R 对映体更具活性。
T12643	(R)-Terazosin (R)-特拉唑嗪,盐酸特拉唑嗪	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	(R)-Terazosin 是一种 Terazosin 的活性 R 型对映体, 是 α1-肾上腺素受体拮抗剂，对 α1a，α1b 和α1d-肾上腺素受体的Ki 分别为 6.51 nM，1.01 nM 和 1.97 nM。
T0197	Terazosin hydrochloride 盐酸特拉唑嗪,Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Terazosin hydrochloride (Hytrin) 是一种竞争性和口服活性的 α1-肾上腺素受体拮抗剂，是一种喹唑啉衍生物。它通过舒张血管和打开膀胱来起作用。它可用于良性前列腺增生和高血压的研究。
T6701	Terazosin hydrochloride dihydrate Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate,盐酸特拉唑嗪(二水合物)	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Terazosin hydrochloride dihydrate (Heitrin dihydrate) 是一种竞争性和口服活性的 α1-肾上腺素受体(α1-adrenoceptor) 拮抗剂，是一种喹唑啉衍生物，通过舒张血管和打开膀胱的方式起作用。它可用于研究良性前列腺增生 (BPH) 和高血压。
T0088	Urapidil hydrochloride Urapidil HCl,盐酸乌拉地尔	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Urapidil hydrochloride (Urapidil HCl) 是α1-肾上腺素受体拮抗剂和5-HT1A 受体激动剂。
T61535	Neldazosin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Neldazosin 可作为一种有效的 α1 肾上腺素受体拮抗剂使用。
T28922	Taprizosin Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Taprizosin（UK-338003）是一种具有选择性和口服活性的 α1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，可用于舒张血管，用于治疗良性前列腺增生症。
T9762	Upidosin SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Upidosin (SB-216469) 是一种有效的、选择性的α1-肾上腺素受体拮抗剂，α1a 亚型Ki=0.34nM，α1b 亚型Ki=3.9nM，β1d 亚型Ki=1.5nM，γ2-肾上腺素受体Ki=33.3nM。
T12597	5-HT2 antagonist 1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2 antagonist 1 是一种有效的 5-HT2 receptor 拮抗剂，同时对 α1 adrenoceptor 有微弱地抑制作用。
T6579	Medetomidine hydrochloride MPV785,Medetomidine HCl,Domitor	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Medetomidine hydrochloride (MPV785) 是一种 α2 肾上腺素受体激动剂，能够作用于α2和α1肾上腺素受体，其Ki 分别为1.08 nM 和1750 nM。
T11015	Midaglizole hydrochloride (±)-DG5128,(±)-DG5128 hydrochloride,DG5128 hydrochloride,DG5128	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Midaglizole hydrochloride ((±)-DG5128) (DG5128) 是有效的 α2-肾上腺素受体拮抗剂。Midaglizole hydrochloride (DG5128) 对 α2-肾上腺素能受体的亲和力 (pKi= 6.28) 比 α1-肾上腺素能受体高 7.4 倍。
T0165	Urapidil Mediatensyl,乌拉地尔,Ebrantil,Eupressyl	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Urapidil (Ebrantil) 是交感神经抗高血压药物，可作为 5-HT1A 受体激动剂和 α1-肾上腺素受体拮抗剂。
T6600	Naftopidil dihydrochloride KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil dihydrochloride (KT-611 2HCl) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T62893	SM-2470	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	SM-2470 是一种α1-adrenoceptor拮抗剂，具有降压活性，可减低前神经节肾上腺神经活性和主动脉降压神经活性。SM-2470 具有降胆固醇活性，可抑制胆固醇吸收。
T23232	Remoxipride hydrochloride Remoxipride Hydrochloride Anhydrous,Roxiam,(S)-Remoxipride Hydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Remoxipride hydrochloride (Roxiam) 是一种选择性的 D2 受体拮抗剂，对 D2 受体、D1 受体和 α1-肾上腺素能受体的 IC50 分别为 1.57 μM、＞100 μM 和 42 μM。
T25828	Monatepil maleate AJ2615 maleate,AJ-2615 maleate,AJ 2615 maleate	Calcium Channel; Adrenergic Receptor; Acyltransferase	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Monatepil maleate (AJ-2615 maleate) 是一种具有口服活性的 Ca2+-通道和α1-肾上腺素受体拮抗剂，也是非竞争性肝酰辅酶A：胆固醇酰基转移酶（ACAT）抑制剂，具有抗高血压活性。Monatepil maleate 可用于研究高脂血症和动脉粥样硬化。
T22232	Alfuzosin SL 77499	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Alfuzosin (SL 77499) 是一种可口服且具有竞争性的 α1-肾上腺素受体拮抗剂。Alfuzosin 诱导膀胱颈和前列腺的平滑肌松弛。Alfuzosin 可用于研究良性前列腺肥大、下尿路症状（LUTS）和射精功能障碍（EjD）。
T9220	Naftopidil hydrochloride 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil hydrochloride (BM-15275 hydrochloride) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力 Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T0696	Naftopidil KT-611,萘哌地尔,BM-15275	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil (KT-611) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM 、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T6466	Dexmedetomidine hydrochloride Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,盐酸右美托咪定,Dexmedetomidine HCl	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Dexmedetomidine hydrochloride (Precedex) 是一种有效的、选择性的、具有口服活性的 α2 肾上腺素能受体 (α2-adrenoceptor) 激动剂，Ki=1.08 nM。它对 α1 肾上腺素受体显示出 1620 倍的选择性。它具有抗焦虑作用，可用于研究促进安定和缓解疼痛。
T22837	HEAT hydrochloride	Others	Others
	HEAT hydrochloride is an α1-adrenoceptor antagonist.
T15042	D2343	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.
T22500	2-PMDQ	Others	Others
	2-PMDQ is an α1-adrenoceptor antagonist.
T69367	Azepexole	Others	Others
	Azepexole is a selective α2-adrenoceptor agonist that exhibits greater than 300-fold selectivity for the α2-adrenoceptor over the α1-adrenoceptor.
T9819	Bunazosin	Others	Others
	Bunazosin 是一种有效的选择性 α1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，可用于降压和降眼压研究。
T11286	Fiduxosin A 185980.1,ABT 980	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Fiduxosin 是一种具有选择性和有效性的 α1-adrenoceptor 拮抗剂，对 α1a-adrenoceptor，α1b-adrenoceptor 和 α1d-adrenoceptor 有抑制作用，Ki 值分别为 0.160 nM，24.9 nM 和 0.920 nM。Fiduxosin 可用于治疗良性前列腺增生。
T35581	Prazobind	Others	Others
	Prazobind 是哌唑嗪类物质，可以阻断胰岛素对 IP1（inositol phosphate）积累的刺激，是一种有效的 α1 肾上腺素受体阻滞剂。
T37817	Terazosin dimer impurity dihydrochloride	Others	Others
	Terazosin dimer impurity dihydrochloride, a dimeric form of Terazosin, is a chemical impurity found in Terazosin. Terazosin itself is a derivative of quinazoline and acts as a competitive and orally active α1-adrenoceptor antagonist[1].
T36949	Niaprazine	5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Niaprazine 是有效的组胺 H1 受体拮抗剂，具有抗组胺和抗血清素活性。Niaprazine 在睡眠障碍方面有研究的价值。
T21492	Medetomidine	Others	Others
	Medetomidine(Domtor)是一种有效的、高选择性的、具有口服活性的α2肾上腺素受体激动剂，对α2和α1肾上腺素受体的 Ki 值分别为1.08 nM 和1750 nM。
T25263	Clopimozide R-29764,NSC-335305,NSC 335305,NSC335305,R 29764	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Clopimozide (R-29764) 可作为一种钙通道拮抗剂，抑制 [3H] 尼群地平结合。Clopimozide 是一种新型且可口服的长效抗精神分裂症精神安定化合物。
T16759	Ritanserin 利坦丝林,R 55667	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Ritanserin (R 55667) 是一种长效、高效、相对选择性、可口服的5-HT2受体拮抗剂，IC50值为 0.9 nM。
T2546	Pimozide R6238,匹莫奇特,匹莫齐特	Potassium Channel; Dopamine Receptor; Adrenergic Receptor; STAT	GPCR/G Protein; JAK/STAT signaling; Membrane transporter/Ion channel; Neuroscience; Stem Cells
	Pimozide (R6238) 是多巴胺受体拮抗剂，对多巴胺 D1、D2 和 D3 受体的 Ki 值分别为 588、1.4 和 2.5 nM。它也是STAT3和STAT5的抑制剂，对 α1 肾上腺素受体也有较高亲和性，Ki 值为 39 nM。
T23396	ST1936 ST 1936 oxalate	5-HT Receptor	GPCR/G Protein; Neuroscience
	ST1936 (ST 1936 oxalate) 是一种具有选择性和高效性的 5-HT6 受体激动剂，抑制人 5-HT6、5-HT7 和 5-HT2B 受体，通过完全激活克隆的人 5-HT6 受体来刺激 cAMP、Ca2+、ERK1/2 和 Fyn 激酶。
T12480	Pipamperone Floropipamide,McN-JR 3345,酰胺哌啶酮,R 3345	Others; Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	Pipamperone (McN-JR 3345) 是5-HT2A 受体和D4受体的高亲和力拮抗剂，也是D2受体的低亲和力拮抗剂，pKi 分别为 8.2、8.0 和 6.7。
T28167	NGB 2904 NGB2904 HCl,NGB-2904,NGB2904	Others; Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience; Others
	NGB 2904 是一种具有口服活性的、选择性的多巴胺(DA) D3受体拮抗剂，可用于具可卡因成瘾。
T10168	5-HT1A modulator 1 5-HT1Amodulator1	Phospholipase; Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Metabolism; Neuroscience
	5-HT1A modulator 1 对 5-HT1A、α1-肾上腺素能受体和 D2 受体具有非常高的亲和力（IC50s = 2 nM、10 nM 和 40 nM）。
T37794	Rec 15/2615 (hydrochloride)	Others	Others
	Rec 15/2615 is an antagonist of α1B-adrenergic receptors (α1B-ARs; Ki = 0.45 nM for the recombinant human receptor).1 It selectively inhibits α1B-ARs over α1A-, α1D-, and α1L-ARs (Kis = 7.59, 10.23, and 49 nM, respectively). Rec 15/2615 inhibits norepinephrine-induced contractions of isolated rabbit prostate and urethral strips (Kis = 100 and 316.2 nM, respectively), as well as reduces norepinephrine-induced contractions of chloroethylclonidine-precontracted isolated rabbit aortic rings (Ki = 50...
T12252	NRA-0160	Dopamine Receptor	GPCR/G Protein; Neuroscience
	NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)
T10360	AR-A 2 AR-A 000002	Others	Others
	AR-A 2 is a selective 5-HT1B receptor antagonist, with a high affinity to guinea pig cortex 5HT1B/1D and recombinant guinea pig 5-HT1B receptors (Ki: 0.24 and 0.47 nM) and with 10-fold lower affinity to guinea pig 5-HT1D receptor (Ki: 5 nM).

化合物

α1 adrenoceptor-MO-1

Cat.No: T10003

Target: Others

Cat.No: T12643

Synonym: (R)-特拉唑嗪,盐酸特拉唑嗪

Target: Adrenergic Receptor

Terazosin hydrochloride

Cat.No: T0197

Synonym: 盐酸特拉唑嗪,Terazosin HCl,Terazosine,Blavin,Hytrin,Zayasel,Fosfomic

Target: Adrenergic Receptor

Terazosin hydrochloride dihydrate

Cat.No: T6701

Synonym: Flotrin dihydrate,Terazosin HCl Dihydrate,Dysalfa dihydrate,Heitrin dihydrate,盐酸特拉唑嗪(二水合物)

Target: Adrenergic Receptor

Urapidil hydrochloride

Cat.No: T0088

Synonym: Urapidil HCl,盐酸乌拉地尔

Target: 5-HT Receptor, Adrenergic Receptor

Cat.No: T61535

Target: Adrenergic Receptor

Cat.No: T28922

Synonym: Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003

Target: Adrenergic Receptor

Cat.No: T9762

Synonym: SB-216469,SB 216469,Rec 15-2739,Recordati 15/2739

Target: Adrenergic Receptor

5-HT2 antagonist 1

Cat.No: T12597

Target: 5-HT Receptor

Medetomidine hydrochloride

Cat.No: T6579

Synonym: MPV785,Medetomidine HCl,Domitor

Target: Adrenergic Receptor

Midaglizole hydrochloride

Cat.No: T11015

Synonym: (±)-DG5128,(±)-DG5128 hydrochloride,DG5128 hydrochloride,DG5128

Target: Adrenergic Receptor

Cat.No: T0165

Synonym: Mediatensyl,乌拉地尔,Ebrantil,Eupressyl

Target: 5-HT Receptor, Adrenergic Receptor

Naftopidil dihydrochloride

Cat.No: T6600

Synonym: KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl

Target: 5-HT Receptor, Adrenergic Receptor

Cat.No: T62893

Target: Adrenergic Receptor

Remoxipride hydrochloride

Cat.No: T23232

Synonym: Remoxipride Hydrochloride Anhydrous,Roxiam,(S)-Remoxipride Hydrochloride

Target: Dopamine Receptor

Monatepil maleate

Cat.No: T25828

Synonym: AJ2615 maleate,AJ-2615 maleate,AJ 2615 maleate

Target: Calcium Channel, Adrenergic Receptor, Acyltransferase

Cat.No: T22232

Synonym: SL 77499

Target: Adrenergic Receptor

Naftopidil hydrochloride

Cat.No: T9220

Synonym: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,萘哌地尔盐酸盐,KT-611 hydrochloride,BM-15275 hydrochloride

Target: Adrenergic Receptor

Cat.No: T0696

Synonym: KT-611,萘哌地尔,BM-15275

Target: Adrenergic Receptor

Dexmedetomidine hydrochloride

Cat.No: T6466

Synonym: Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,盐酸右美托咪定,Dexmedetomidine HCl

Target: Adrenergic Receptor

HEAT hydrochloride

Cat.No: T22837

Target: Others

Cat.No: T15042

Target: Adrenergic Receptor

Cat.No: T22500

Target: Others

Cat.No: T69367

Target: Others

Cat.No: T9819

Target: Others

Cat.No: T11286

Synonym: A 185980.1,ABT 980

Target: Adrenergic Receptor

Cat.No: T35581

Target: Others

Terazosin dimer impurity dihydrochloride

Cat.No: T37817

Target: Others

Cat.No: T36949

Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Cat.No: T21492

Target: Others

Cat.No: T25263

Synonym: R-29764,NSC-335305,NSC 335305,NSC335305,R 29764

Target: Calcium Channel

Cat.No: T16759

Synonym: 利坦丝林,R 55667

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Histamine Receptor

Cat.No: T2546

Synonym: R6238,匹莫奇特,匹莫齐特

Target: Potassium Channel, Dopamine Receptor, Adrenergic Receptor, STAT

Cat.No: T23396

Synonym: ST 1936 oxalate

Target: 5-HT Receptor

Cat.No: T12480

Synonym: Floropipamide,McN-JR 3345,酰胺哌啶酮,R 3345

Target: Others, Dopamine Receptor, 5-HT Receptor

Cat.No: T28167

Synonym: NGB2904 HCl,NGB-2904,NGB2904

Target: Others, Dopamine Receptor, 5-HT Receptor

5-HT1A modulator 1

Cat.No: T10168

Synonym: 5-HT1Amodulator1

Target: Phospholipase, Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor

Rec 15/2615 (hydrochloride)

Cat.No: T37794

Target: Others

Cat.No: T12252

Target: Dopamine Receptor

Cat.No: T10360

Synonym: AR-A 000002

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T17310	Phenylephrine 去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Phenylephrine ((R)-(-)-Phenylephrine) 是一种选择性的α1-肾上腺素受体激动剂，常用作减充血剂。
T8044	Ajmalicine 阿吗里新,Lamuran,Delta-Yohimbine,Raubasine,Ajmalicin	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Ajmalicine (Raubasine) 是一种有效的抗肾上腺素 (adrenolytic) 剂，优先阻断 α1-肾上腺素受体 (α1-adrenoceptor)。Ajmalicine 是一种可逆性但非竞争性尼古丁受体 (nicotine receptor) 完全抑制剂，IC50 为 72.3 μM。Ajmalicine 还可用于降压、蛇毒，具有镇静活性。
T13655	DL-Norepinephrine hydrochloride 去甲肾上腺素盐酸盐,Lys,DL-lysine	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	DL-Norepinephrine hydrochloride (DL-lysine) 是一种靶向α1 adrenoceptor 和β1 adrenoceptor 的神经递质，可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T7044	Norepinephrine 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol	MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy	Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome
	Norepinephrine (Levophed) 属于生物碱类天然产物，是一种神经递质，一种肾上腺素能受体 (AR) 的激动剂，对 α1、α2 和 β1 AR 具有激活活性。Norepinephrine 被用作抗休克的血管活性剂。
T2889	Isoferulic acid Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸	Influenza Virus; Adrenergic Receptor	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Isoferulic acid (Hesperetate) 是一种肉桂酸衍生物，有抗糖尿病活性和抗流感病毒活性。它能结合并激活 α1-肾上腺素能受体，增强 β-内啡肽的分泌并增加体外葡萄糖的使用。
T69254	Ajmalicine hydrochloride Raubasine hydrochloride	Others	Others
	Ajmalicine (Raubasine) hydrochloride 是一种有效的抗肾上腺素 (adrenolytic) 剂，优先阻断 α1-肾上腺素受体 (α1-adrenoceptor)。Ajmalicine hydrochloride 是一种可逆性但非竞争性尼古丁受体 (nicotine receptor) 完全抑制剂，其 IC50为 72.3 μM。Ajmalicine hydrochloride 还可用于降压、蛇毒，具有镇静活性。

天然产物

Cat.No: T17310

Synonym: 去氧肾上腺素,L-Phenylephrine,去氧肾上腺素碱,(R)-(-)-Phenylephrine

Target: Adrenergic Receptor

Cat.No: T8044

Synonym: 阿吗里新,Lamuran,Delta-Yohimbine,Raubasine,Ajmalicin

Target: Adrenergic Receptor

DL-Norepinephrine hydrochloride

Cat.No: T13655

Synonym: 去甲肾上腺素盐酸盐,Lys,DL-lysine

Target: Adrenergic Receptor

Cat.No: T7044

Synonym: 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy

Isoferulic acid

Cat.No: T2889

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate,异阿魏酸

Target: Influenza Virus, Adrenergic Receptor

Ajmalicine hydrochloride

Cat.No: T69254

Synonym: Raubasine hydrochloride

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01534	Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi) RING12,PSMB9,Proteasome chain 7,RMF,LMP-2,LMP2,MHC,Macropain...	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01523	Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi) WAGR,WT33,AWT1,GUD,RMF,WT1,WIT-2,MHC,NPHS4GUD	Human & Mouse	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.
TMPK-01535	Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi) Macropain chain 7,LMP2,Proteasome chain 7,RING12,PSMB9,MHC,R...	Human & Mouse	HEK293 Cells
	The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of ma...
TMPK-01522	Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi) RMF,WT33,WIT-2,MHC,WAGR,AWT1,GUD,WT1,NPHS4GUD	Human & Mouse	HEK293 Cells
	The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, endometrioid, clear cell, and mucinous carcinomas of the peritoneum, fallopian tube, ovary, and endometrium.The Human HLA-A0201 WT-1 (RMFPNAPYL) complex Protein is a complex of HLA-A0201 of the MHC Class I, B2M and RMFPNAPYL peptide of the WT-1.

重组蛋白

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01534

Species: Human & Mouse

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Monomer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01523

Species: Human & Mouse

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&LMP2 (CLGGLLTMV) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01535

Species: Human & Mouse

Expression System: HEK293 Cells

Chimeric HLA-A*02:01 (mα3) &B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human&Mouse, MHC (His & Avi)

Cat.No: TMPK-01522

Species: Human & Mouse

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0206	(R)-(-)-Phenylephrine-2,4,6-d3
	(R)-(-)-Phenylephrine-2,4,6-d3 是 (R)-(-)-Phenylephrine 的氘代化合物。(R)-(-)-Phenylephrine 的 CAS 号为 59-42-7。Phenylephrine 是一种选择性的α1-肾上腺素受体激动剂，常用作减充血剂。
TMIJ-0183	Terazosin-d8
	Terazosin-d8 是 Terazosin 的氘代化合物。Terazosin 的 CAS 号为 63590-64-7。
TMIJ-0055	DL-Norepinephrine-d6 HCl
	DL-Norepinephrine-d6 HCl 是 DL-NorepinephrineHCl 的氘代化合物。DL-NorepinephrineHCl 的 CAS 号为 55-27-6。DL-Norepinephrine hydrochloride 是一种靶向α1 adrenoceptor和β1 adrenoceptor的神经递质，可降低心内膜下氧分压。它是一种模拟内源性去甲肾上腺素的拟交感神经作用的合成苯乙胺。
T12476	Pimozide-d4 Pimozide D4,R6238 D4	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Pimozide D4 is a deuterium labeled Pimozide.

同位素标记化合物

(R)-(-)-Phenylephrine-2,4,6-d3

Cat.No: TMIJ-0206

Cat.No: TMIJ-0183

DL-Norepinephrine-d6 HCl

Cat.No: TMIJ-0055

Cat.No: T12476

Synonym: Pimozide D4,R6238 D4

Target: Dopamine Receptor

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