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Search Results for " ?plaque "

Targets Recommended: Prostaglandin Receptor

45

抑制剂 & 化合物

3

天然产物

18

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T15108	DG-041	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	DG-041 是高亲和力，选择性的，有效的 EP3受体拮抗剂，在结合和 FLIPR 试验中，IC50分别为 4.6 nM 和 8.1 nM。DG-041通过抑制 PGE2促进血小板聚集。DG-041具有血脑屏障渗透性。
T0328	Hexetidine NSC-17764,海克替啶	Antibacterial; Antifungal	Microbiology/Virology
	Hexetidine (NSC-17764) 是一种口服活性的抗菌抗真菌试剂，可用于口腔感染的相关研究。
T14369	AZD-0284	ROR	Metabolism
	AZD-0284 是核受体 (RORγ) 的选择性反向激动剂。它对呼吸道疾病及斑块型寻常型银屑病具有潜在的应用价值。
T7657	MOG (35-55) mouse, rat 髓鞘少突胶质细胞糖蛋白,MOG (35-55)	Others	Others
	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) 是中枢神经鞘的一个次要成分。它能诱导强效的 T 细胞和 B 细胞反应，同时是高度脑源性的。它能够引发复发缓解性神经系统疾病，伴有广泛的斑块样脱髓鞘。
TP2045	CH 275
	Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin release in the rat nucleus accumbens
T1000L	Chlorhexidine diacetate 醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras	CAT; Antibacterial; Antibiotic; Antifection	Microbiology/Virology; oxidation-reduction
	Chlorhexidine diacetate (Bactigras) 是一种双胍类杀菌剂，能快速消灭革兰氏阳性菌和革兰氏阴性菌。它也用作漱口水以防止口腔菌斑。
T1147	Chlorhexidine dihydrochloride 盐酸氯己定,Chlorhexidine hydrochloride,Chlorhexidine 2HCl,NSC-185	CAT; Cell wall; Antibacterial; Antibiotic; Antifection	Immunology/Inflammation; Microbiology/Virology; oxidation-reduction
	Chlorhexidine dihydrochloride (NSC-185) 是一种消毒剂和局部抗感染剂，也用作漱口水以防止口腔菌斑。
T68006	Orilotimod potassium APO805K1	Others	Others
	Orilotimod potassium (APO805K1)可用于研究斑块状银屑病。
T77665	ZINC40099027 ZINC-40099027,ZINC 40099027	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	ZINC40099027 是特异性黏着斑激酶（FAK）激活剂，通过激活黏着斑激酶促进持续性阿司匹林相关胃损伤的胃粘膜修复，通过加速FAK激酶结构域的酶活性来激活人黏着斑激酶，激活细胞 FAK 并促进肠上皮伤口闭合。
T9930	Secukinumab 苏金单抗,司库奇尤单抗	IL Receptor	Immunology/Inflammation
	Secukinumab 是一种完全人源化的单克隆抗 IL-17A 抗体，是一个被美国食品和药物管理局批准用于治疗中度至重度斑块型银屑病的抗体。
T17038	Tepilamide fumarate XP-23829	Others	Others
	Tepilamide fumarate (XP-23829) 是一种口服具有活性的延胡索酸酯，可用于研究中度到重度慢性斑块银屑病。
T60921L	PF-07038124 HCl PF-07038124 HCl（2415085-44-6 Free base)	IL Receptor; PDE	Immunology/Inflammation; Metabolism
	PF-07038124 HCl 是一种具有选择性和高效性的 PDE4 抑制剂，对 PDE4B2 的 IC50 为0.5 nM。PF-07038124 HCl 抑制 IL-13、IL-4 和 IFNγ，可用于研究特应性皮炎和斑块状银屑病等皮肤疾病。
T76953	Xeligekimab GR 1501,GR-1501,GR1501	IL Receptor	Immunology/Inflammation
	Xeligekimab (GR 1501) 是一种选择性中和 IL-17A 的全人源单克隆抗体，具有潜在的抗炎活性，可用于研究斑块状银屑。
T77170	Siplizumab MEDI-507	Others	Others
	Siplizumab (MEDI-507) 是一种人源化靶向 CD2 的 IgG1 单克隆抗体。Siplizumab 在体外选择性地消耗效应记忆 T 细胞并促进同种异体反应性调节性 T 细胞的相对扩增。Siplizumab 可用于治疗斑块状银屑病。
T16094	MK-3328	Others	Others
	MK-3328 是对β-淀粉样蛋白 (β-Amyloid)具有很高的亲和力(IC50 为 10.5 nM）,是一种可作为临床评估β-淀粉样斑块负荷的候选 PET 配体。MK-3328是治疗阿尔茨海默病的潜在药物。
T0305	Erythrosine B Erythrosine I,Erythrosin extra bluish,Erythrosin B,赤藓红B	Others	Others
	Erythrosine B (Erythrosine I) 是一种已被用于开发动物模型的新型光敏剂，在食品和纺织工业的人造染料中具有广泛的应用。
T37445	Etanercept	TNF	Apoptosis
	Etanercept is a dimeric fusion protein that serves as a competitive TNF inhibitor by binding to TNF. It effectively inhibits the binding of both TNF-α and TNF-β to the TNF receptors on cell surfaces, thereby rendering TNF biologically inactive. Etanercept has demonstrated efficacy in treating rheumatoid arthritis, juvenile idiopathic arthritis, and plaque psoriasis.
T0578	Erythrosin B Iodeosin,Tetraiodofluorescein,藻红B	Others	Others
	Erythrosin B (Iodeosin) 是一种四碘荧光素，在某些食物（樱桃、鱼）中用作红色色素，用作某些细胞类型的染色剂，以及用作牙菌斑的披露物。其分子结构与甲状腺素相似。
T38105	Ixekizumab LY2439821	IL Receptor; Interleukin	Immunology/Inflammation
	Ixekizumab (LY2439821) 是一种人源化 IgG4 单克隆抗体，可选择性结合和中和白细胞介素 IL-17A ，Kd 值<3 pM。Ixekizumab 科阻断 IL-17A 与 IL-17RA 的结合，但不与其他 IL-17 家族成员结合。Ixekizumab 用于治疗中重度斑块型银屑病、银屑病关节炎和牛皮癣。
T64167	Ifebemtinib IN-10018,BI-853520	FAK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Ifebemtinib (BI-853520) 是一种具有口服活性和强效性的粘附斑激酶 (FAK) 抑制剂 (IC50=1 nM)，具有抗肿瘤活性，可抑制恶性胸膜间皮瘤中的球状体形成和原位肿瘤生长，可用于研究乳腺癌和卵巢癌。
T0900	Cetylpyridinium chloride monohydrate Hexadecylpyridinium chloride monohydrate,十六烷基氯化吡啶	Antibacterial; Antibiotic	Microbiology/Virology
	Cetylpyridinium chloride monohydrate (Hexadecylpyridinium chloride monohydrate) 是阳离子季铵, 是一种能杀死细菌和其他微生物的防腐剂, 用于某些类型的漱口水, 牙膏, 咽喉和鼻腔喷雾剂中, 可有效预防牙斑和减少牙龈炎。
T76924	Efalizumab Hu1124,HU 1124	Integrin	Cytoskeletal Signaling
	Efalizumab 是一种新型针对 T 细胞的有效调节剂，是人源化 LFA-1 α 亚基（CD11a）单克隆抗体。Efalizumab 对 T 细胞激活、皮肤T细胞运输和T细胞粘附到角质形成细胞有抑制作用，可用于研究斑块银屑病和银屑病关节炎。
T68705	Salifluor	Others	Others
	Salifluor is a broad spectrum antimicrobial agent that has been investigated for its abilities to inhibit dental plaque formation.
T1267L	Abacavir acetate KM-133,KM133,KM 133	Others	Others
	Abacavir acetate (Prurisol) has the potential to be used in the treatment of plaque psoriasis.
T41336	Chlorhexidine acetate hydrate
	Chlorhexidine acetate hydrate 是一种消毒剂和局部抗感染剂，也用作漱口水以防止口腔菌斑。
TP1494	β-Amyloid (4-10) β-Amyloid 4-10
	Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in mice. This peptide does not elicit an inflammatory response.
T68494	Octenidine saccharin	Others	Others
	Octenidine saccharin is a Dental Plaque Inhibitor
T38175	MPro N3	Others	Others
	Coronavirus main protease (Mpro) inhibitor (respective IC50 values are 2.7, 4 and 8.8 μM for MHV-A29, HCoV-229E and FOPV replication in vitro). Inhibits viral cell infection in an MHV plaque reduction assay. Also inhibits SARS-CoV-2 viral cell entry in a plaque reduction assay (IC50 = 16.8 μM).
T77098	Netakimab
	Netakimab为抗IL-17单克隆抗体。Nerelimomab适用于研究强直性脊柱炎、银屑病关节炎及中重度斑块状银屑病。
T69456	Melagatran monohydrate	Others	Others
	Melagatran monohydrate is a thrombin inhibitor. Melagatran prevents tissue factor expression in human platelet-monocyte heterotypic complexes. Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient mice.
T78298	Alefacept LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273
	Alefacept (BG 9273)为一种人类淋巴细胞功能相关抗原3/免疫球蛋白1融合蛋白，主要在慢性斑块状银屑病研究中使用。
T76885	Sonelokimab
	Sonelokimab (ALX 0761; M 1095) 是三价纳米抗体，特异性结合人白介素(IL)-17A、IL-17F及人血清白蛋白VHH，由单价骆驼来源纳米抗体构成，展现于斑块型银屑病研究中的应用潜力。
T21814	ONO 4817	Others	Others
	ONO-4817 是一种广谱基质金属蛋白酶 (MMP) 抑制剂。抑制基质金属蛋白酶 (MMP) 有望抑制动脉粥样硬化新内膜增殖，从而限制动脉粥样硬化斑块的进展。ONO-4817 抑制实验性高脂血症兔主动脉内膜增生的发展。
T69664	Umibecestat HCl	Others	Others
	Umibecestat, also known as CNP-520, is a beta-secretase inhibitor and is a drug candidate for prevention trials in Alzheimer's disease. CNP520 has a selectivity, pharmacodynamics, and distribution profile suitable for AD prevention studies. CNP520 reduced brain and cerebrospinal fluid (CSF) Aβ in rats and dogs, and Aβ plaque deposition in APP-transgenic mice. CNP520 reduces Aβ load and neuroinflammation in APP‐transgenic mice
TP2135	cAC 253
	Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's disease model.
TP2171	β-amyloid (12-28) (TFA) (107015-83-8 free base) Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)	Others	Others
	β-amyloid (12-28) TFA, a peptide fragment of β-amyloid protein (β1-42), is the major component of senile plaque cores. β-amyloid (12-28) has aggregation properties and the potential for Alzheimer’s disease research.
T84987	3′-deoxy Thymidine 2',3'-Dideoxythymidine	Others	Others
	d2T, a nucleoside analog of thymidine, exhibits antiviral activity by inhibiting HIV replication in infected human peripheral blood mononuclear cells (PBMCs; EC50 = 0.17 µM). Additionally, 3′-deoxy Thymidine at concentrations of 1, 3, 10, or 30 µM significantly decreases viral plaque formation in CV-1 cells infected with herpes simplex virus 1 (HSV-1).
T63558	IRAK4-IN-21	Others	Others
	IRAK4-IN-21 是选择性的、口服具有活力的、强效的 IRAK4 抑制剂，能够作用于 IRAK4 (IC50: 5 nM) 和 TAK1 (IC50: 56 nM)。IRAK4-IN-21 对 IL-23 的产生表现出有效的抑制作用，其 IC50值为0.17 μM。IRAK4-IN-21 能够用于研究自身免疫性疾病，如斑块状银屑病和银屑病关节炎。
T75779	β-Amyloid (12-28) (TFA)
	β-Amyloid (12-28) (TFA)为β-淀粉样蛋白(β1-42)的肽片段，后者是由42个氨基酸组成，构成老年斑核心的关键蛋白。β-Amyloid (12-28) (TFA)展现出聚集性质，并可能对阿尔茨海默氏病研究具有潜在价值。
T78541	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA MOG (35-55) (TFA)
	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) TFA 是一种具有致脑炎活性的化合物，能够诱导 T 细胞增殖和 Th1 细胞因子反应，并促使产生相对较高水平的 IgG 抗体。此化合物作为中枢神经鞘的次要成分，可触发带有广泛斑块样脱髓鞘的复发缓解性神经系统疾病。
T72893	AChE/MAO-IN-2	Others	Others
	Dual AChE-MAO B-IN-5 是一种茚满酮衍生物，是一种有效的双重 AChE/MAO-B 抑制剂，对 AChE、MAO-B 和 MAO-A 的IC50值分别为 0.0224、0.0412 和 0.1116 μM。Dual AChE-MAO B-IN-5 具有抗氧化活性，防止 β-淀粉样斑块聚集。Dual AChE-MAO B-IN-5 可用于阿尔茨海默病 (AD) 研究。
T63559	IRAK4-IN-22	Others	Others
	IRAK4-IN-22 是选择性的、口服具有活力的、强效的 IRAK4 抑制剂，能够作用于 IRAK4 (IC50: 3 nM) 和 TAK1 (IC50: 17 nM)。IRAK4-IN-21 对 IL-23 的产生表现出有效的抑制作用，其 IC50值为0.10 μM。IRAK4-IN-21 能够用于研究自身免疫性疾病，如斑块状银屑病和银屑病关节炎。
T78542	Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate MOG (35-55) (acetate)
	Myelin Oligodendrocyte GlycoproteinPeptide (35-55), mouse, rat (MOG (35-55)) acetate 是一中枢神经系统髓鞘的非主要成分，它显示出致脑炎活性，并能诱导 T 细胞增殖。此外，MOG (35-55) acetate 能够诱导 Th1 细胞因子反应，并促使相对高水平的 IgG 抗体生成。它也可能引起复发性和缓解性的神经系统疾病，并伴随广泛的斑块样脱髓鞘现象。
T83710	Gastric Inhibitory Peptide (22-51) (human) TFA GIP (22-51),Glucose-dependent Insulinotropic Peptide (22-51)
	胃抑制肽(GIP) (22-51) 是一种具有30个氨基酸的前动脉硬化肽，对应于GIP前体蛋白proGIP的第22至51个氨基酸残基，已在人类血浆中发现。在1 µM的浓度下使用，该肽能引起在巨峰细胞分化的THP-1细胞和分离的人类主动脉内皮细胞中IκB-α的降解和NF-κB的核转移。在体内，GIP (22-51) 增加了ApoE-/-小鼠的动脉粥样硬化病变面积和斑块形成。
T72454	AChE/BChE/MAO-B-IN-4	Others	Others
	AChE/BChE/MAO-B-IN-4 是一种 1-茚满酮衍生物，是一种有效的MAO-B 抑制剂，对人MAO-B 的IC50为 0.0359 μM。AChE/BChE/MAO-B-IN-4 是一种有效的AChE 和BChE 酶抑制剂，对人AChE 和BChE 酶的IC50值分别为 0.0473 μM 和 0.0782 μM。AChE/BChE/MAO-B-IN-4 显示出显着的抗氧化活性，并防止β-淀粉样蛋白斑块聚集。AChE/BChE/MAO-B-IN-4 具有用于阿尔茨海默病 (AD) 研究的潜力。

化合物

Cat.No: T15108

Target: Prostaglandin Receptor

Cat.No: T0328

Synonym: NSC-17764,海克替啶

Target: Antibacterial, Antifungal

Cat.No: T14369

Target: ROR

MOG (35-55) mouse, rat

Cat.No: T7657

Synonym: 髓鞘少突胶质细胞糖蛋白,MOG (35-55)

Target: Others

Cat.No: TP2045

Chlorhexidine diacetate

Cat.No: T1000L

Synonym: 醋酸氯己定,Hibitane diacetate,Chlorhexidine Acetate,Bactigras

Target: CAT, Antibacterial, Antibiotic, Antifection

Chlorhexidine dihydrochloride

Cat.No: T1147

Synonym: 盐酸氯己定,Chlorhexidine hydrochloride,Chlorhexidine 2HCl,NSC-185

Target: CAT, Cell wall, Antibacterial, Antibiotic, Antifection

Orilotimod potassium

Cat.No: T68006

Synonym: APO805K1

Target: Others

Cat.No: T77665

Synonym: ZINC-40099027,ZINC 40099027

Target: FAK

Cat.No: T9930

Synonym: 苏金单抗,司库奇尤单抗

Target: IL Receptor

Tepilamide fumarate

Cat.No: T17038

Synonym: XP-23829

Target: Others

PF-07038124 HCl

Cat.No: T60921L

Synonym: PF-07038124 HCl（2415085-44-6 Free base)

Target: IL Receptor, PDE

Cat.No: T76953

Synonym: GR 1501,GR-1501,GR1501

Target: IL Receptor

Cat.No: T77170

Synonym: MEDI-507

Target: Others

Cat.No: T16094

Target: Others

Cat.No: T0305

Synonym: Erythrosine I,Erythrosin extra bluish,Erythrosin B,赤藓红B

Target: Others

Cat.No: T37445

Target: TNF

Cat.No: T0578

Synonym: Iodeosin,Tetraiodofluorescein,藻红B

Target: Others

Cat.No: T38105

Synonym: LY2439821

Target: IL Receptor, Interleukin

Cat.No: T64167

Synonym: IN-10018,BI-853520

Target: FAK

Cetylpyridinium chloride monohydrate

Cat.No: T0900

Synonym: Hexadecylpyridinium chloride monohydrate,十六烷基氯化吡啶

Target: Antibacterial, Antibiotic

Cat.No: T76924

Synonym: Hu1124,HU 1124

Target: Integrin

Cat.No: T68705

Target: Others

Abacavir acetate

Cat.No: T1267L

Synonym: KM-133,KM133,KM 133

Target: Others

Chlorhexidine acetate hydrate

Cat.No: T41336

β-Amyloid (4-10)

Cat.No: TP1494

Synonym: β-Amyloid 4-10

Octenidine saccharin

Cat.No: T68494

Target: Others

Cat.No: T38175

Target: Others

Cat.No: T77098

Melagatran monohydrate

Cat.No: T69456

Target: Others

Cat.No: T78298

Synonym: LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273

Cat.No: T76885

Cat.No: T21814

Target: Others

Umibecestat HCl

Cat.No: T69664

Target: Others

Cat.No: TP2135

β-amyloid (12-28) (TFA) (107015-83-8 free base)

Cat.No: TP2171

Synonym: Amyloid β-Protein (12-28) (TFA),β-amyloid (12-28) (TFA)

Target: Others

3′-deoxy Thymidine

Cat.No: T84987

Synonym: 2',3'-Dideoxythymidine

Target: Others

Cat.No: T63558

Target: Others

β-Amyloid (12-28) (TFA)

Cat.No: T75779

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA

Cat.No: T78541

Synonym: MOG (35-55) (TFA)

Cat.No: T72893

Target: Others

Cat.No: T63559

Target: Others

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat acetate

Cat.No: T78542

Synonym: MOG (35-55) (acetate)

Gastric Inhibitory Peptide (22-51) (human) TFA

Cat.No: T83710

Synonym: GIP (22-51),Glucose-dependent Insulinotropic Peptide (22-51)

AChE/BChE/MAO-B-IN-4

Cat.No: T72454

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T4723	D-Tagatose 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos	Others; Endogenous Metabolite	Metabolism; Others
	D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖，具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物，也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品，也是口香糖、果汁和饮料等食品中的低热量甜味剂。
TN7506	(−)-β-Sesquiphellandrene (−)-βSesquiphellandrene,(−)-β Sesquiphellandrene,(−)βSesquiphellandrene,(−)β-Sesquiphellandrene,(−) β Sesquiphellandrene,(−) β-Sesquiphellandrene	Others	Others
	(–)-β-Sesquiphellandrene, a sesquiterpene identified in Z. officinale, exhibits antiviral and anticancer properties. It effectively inhibits rhinovirus IB virus replication in a plaque reduction assay with an IC50 of 0.44 µM. Additionally, at a concentration of 10 µM, it demonstrates cytotoxicity to HCT116 cells.
T38015	Herquline A	Others	Others
	Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively).

天然产物

Cat.No: T4723

Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Target: Others, Endogenous Metabolite

(−)-β-Sesquiphellandrene

Cat.No: TN7506

Synonym: (−)-βSesquiphellandrene,(−)-β Sesquiphellandrene,(−)βSesquiphellandrene,(−)β-Sesquiphellandrene,(−) β Sesquiphellandrene,(−) β-Sesquiphellandrene

Target: Others

Cat.No: T38015

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03660	Vaccinia virus (strain Lister) OPG190 Protein (His) OPG190,Protein OPG190,Plaque-size/host range protei...	VACV	E. coli
	Regulation of plaque size and host range. Vaccinia virus (strain Lister) OPG190 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is P24083.
TMPH-03668	Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His) OPG190,Plaque-size/host range protein,Protein OPG19...	VACV	E. coli
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.2 kDa and the accession number is Q01227.
TMPH-03667	Vaccinia virus (strain Copenhagen) OPG190 Protein (His) Plaque-size/host range protein,Protein OPG190,OPG19...	VACV	P. pastoris (Yeast)
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracellular enveloped virions (IEV). Vaccinia virus (strain Copenhagen) OPG190 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is P21115.
TMPH-03666	Vaccinia virus (strain Copenhagen) OPG190 Protein (His & Myc) Plaque-size/host range protein,OPG190,Protein OPG19...	VACV	E. coli
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EEV) to allow virion entry into host cells. Participates also in wrapping intracellular mature virions (IMV) to form intracellular enveloped virions (IEV). Vaccinia virus (strain Copenhagen) OPG190 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 36.5 kDa and the accession number is P21115.
TMPH-03669	Vaccinia virus (strain Western Reserve) OPG190 Protein (His) OPG190,Plaque-size/host range protein,Protein OPG19...	VACV	P. pastoris (Yeast)
	Plays a role in the dissolution of the outermost membrane of extracellular enveloped virions (EV) to allow virion entry into host cells. Participates also in wrapping mature virions (MV) to form enveloped virions (EV). Vaccinia virus (strain Western Reserve) OPG190 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 31.1 kDa and the accession number is Q01227.
TMPH-03679	Vaccinia virus (strain LC16m8) B5 Protein (E. coli, His) Protein B5,PS/HR,Truncated plaque-size/host range p...	VACV	E. coli
	Regulation of plaque size and host range. In this strain the truncated ps/hr protein is probably not functional. Vaccinia virus (strain LC16m8) B5 Protein (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 14.1 kDa and the accession number is P24284.
TMPH-03680	Vaccinia virus (strain LC16m8) B5 Protein (His) PS/HR,Protein B5,Truncated plaque-size/host range p...	VACV	P. pastoris (Yeast)
	Regulation of plaque size and host range. In this strain the truncated ps/hr protein is probably not functional. Vaccinia virus (strain LC16m8) B5 Protein (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.6 kDa and the accession number is P24284.
TMPH-01217	DSG3 Protein, Human, Recombinant (E. coli, His) 130 kDa pemphigus vulgaris antigen (PVA),CDHF6,DSG3,Cadherin...	Human	E. coli
	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
TMPH-01216	DSG1 Protein, Human, Recombinant (His & Myc) Cadherin family member 4,DGI,Pemphigus foliaceus antigen,CDH...	Human	E. coli
	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
TMPH-02624	Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO) Desmoglein-1,DGI,Dsg1a,Dsg1,Desmosomal glycoprotein I,Dsg1-a...	Mouse	E. coli
	Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 77.2 kDa and the accession number is Q61495.
TMPH-02330	Zyxin Protein, Human, Recombinant (His) Zyxin-2,ZYX,Zyxin	Human	HEK293 Cells
	Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
TMPH-03600	Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc) gtfC,Glucosyltransferase-SI,Dextransucrase,Sucrose 6-glucosy...	Streptococcus mutans	E. coli
	Production of extracellular glucans, that are thought to play a key role in the development of the dental plaque because of their ability to adhere to smooth surfaces and mediate the aggregation of bacterial cells and food debris. Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is P13470.
TMPJ-01312	TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc) Fibroblast growth factor-regulated protein 2,TNFRSF12,Tumor ...	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inf...
TMPY-00319	GIP Protein, Human, Recombinant (hFc) gastric inhibitory polypeptide,GIP	Human	HEK293 Cells
	Glucose-dependent insulinotropic polypeptide (GIP) is an incretin that plays an important role in fat accumulation. GIP is involved in fat accumulation and insulin resistance with aging. Glucose-dependent insulinotropic polypeptide (GIP) is an intestinal hormone with a broad range of physiological actions. Elevated concentrations of the incretin hormone GIP are found in patients with atherosclerotic cardiovascular disease, while GIP treatment attenuates atherosclerotic plaque inflammation in mi...
TMPJ-00362	MMP-2 Protein, Human, Recombinant (His) 72 kDa Gelatinase,TBE-1,Gelatinase A,Matrix Metalloproteinas...	Human	HEK293 Cells
	72 kDa type IV collagenase also known as matrix metalloproteinase-2 (MMP-2) and gelatinase A is an enzyme that in humans is encoded by the MMP2 gene.It belongs to the matrix metalloproteinase (MMP) family. Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis and tissue remodeling, as well as pathologic...
TMPH-01256	Dystonin Protein, Human, Recombinant (His & SUMO) DT,DST,BPAG1,BP240,BP230,KIAA0728,Dystonin,DMH	Human	E. coli
	Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo...
TMPH-01257	Dystonin Protein, Human, Recombinant (His) DT,BP230,Dystonin,BP240,DST,DMH,BPAG1,KIAA0728	Human	P. pastoris (Yeast)
	Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transpo...
TMPY-01249	Cathepsin V Protein, Human, Recombinant (His) CTSV,cathepsin V,MGC125957,CATL2,CTSU,CTSL2	Human	HEK293 Cells
	Cathepsin V (CTSV), also known as Cathepsin L2, CTSL2, and CATL2, is a member of the peptidase C1 family. It is predominantly expressed in the thymus and testis. Cathepsin V is also expressed in corneal epithelium, and to a lesser extent in conjuctival epithelium and skin. It is a lysosomal cysteine proteinase that may play an important role in corneal physiology. It has about 75% protein sequence identity to murine cathepsin L. The fold of this enzyme is similar to the fold adopted by other mem...

重组蛋白

Vaccinia virus (strain Lister) OPG190 Protein (His)

Cat.No: TMPH-03660

Species: VACV

Expression System: E. coli

Vaccinia virus (strain Western Reserve) OPG190 Protein (E. coli, His)

Cat.No: TMPH-03668

Species: VACV

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG190 Protein (His)

Cat.No: TMPH-03667

Species: VACV

Expression System: P. pastoris (Yeast)

Vaccinia virus (strain Copenhagen) OPG190 Protein (His & Myc)

Cat.No: TMPH-03666

Species: VACV

Expression System: E. coli

Vaccinia virus (strain Western Reserve) OPG190 Protein (His)

Cat.No: TMPH-03669

Species: VACV

Expression System: P. pastoris (Yeast)

Vaccinia virus (strain LC16m8) B5 Protein (E. coli, His)

Cat.No: TMPH-03679

Species: VACV

Expression System: E. coli

Vaccinia virus (strain LC16m8) B5 Protein (His)

Cat.No: TMPH-03680

Species: VACV

Expression System: P. pastoris (Yeast)

DSG3 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01217

Species: Human

Expression System: E. coli

DSG1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01216

Species: Human

Expression System: E. coli

Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-02624

Species: Mouse

Expression System: E. coli

Zyxin Protein, Human, Recombinant (His)

Cat.No: TMPH-02330

Species: Human

Expression System: HEK293 Cells

Glucosyltransferase-SI Protein, S. mutans serotype c, Recombinant (His & Myc)

Cat.No: TMPH-03600

Species: Streptococcus mutans

Expression System: E. coli

TWEAKR/TNFRSF12A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-01312

Species: Mouse

Expression System: HEK293 Cells

GIP Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00319

Species: Human

Expression System: HEK293 Cells

MMP-2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00362

Species: Human

Expression System: HEK293 Cells

Dystonin Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01256

Species: Human

Expression System: E. coli

Dystonin Protein, Human, Recombinant (His)

Cat.No: TMPH-01257

Species: Human

Expression System: P. pastoris (Yeast)

Cathepsin V Protein, Human, Recombinant (His)

Cat.No: TMPY-01249

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
T71306	Gemfibrozil-d6
	Gemfibrozil-d6 is intended for use as an internal standard for the quantification of gemfibrozil by GC- or LC-MS. Gemfibrozil is a peroxisome proliferator-activated reporter α and PPARγ agonist. In vivo, gemfibrozil reduces serum total cholesterol, triglyceride, and LDL levels in a rat model of high-cholesterol diet-induced hyperlipidemia. Gemfibrozil reduces atherosclerotic plaque area, superoxide production, and expression of the genes encoding the NF-κB subunit p65 and chemokine (C-C) motif l...
T38118	Zanamivir-13C,15N2 Zanamivir-13C,15N2
	Zanamivir-13C,15N2is intended for use as an internal standard for the quantification of zanamivir by GC- or LC-MS. Zanamivir is a sialic acid analog that inhibits neuraminidase release of newly replicated influenza virus particles.1It has been shown to selectively inhibit the growth of influenza A and B viruses in plaque reduction assays with IC50values ranging from 5 to 14 nM and to directly inhibit influenza A and B virus neuraminidases with IC50values ranging from 0.6 to 7.9 nMin vitro. Intra...
TMID-0170	Homotaurine-d6
	Homotaurine-d6 是 Homotaurine 的氘代化合物。Homotaurine 的 CAS 号为 3687-18-1。Homotaurine 是一种具有口服活性的、可透过血脑屏障的天然氨基酸，存在于各种红色海藻中，能够可溶性 Aβ 结合并以非原纤维形式维持 Aβ。它是一种 GABA 类似物，具有神经保护，抗惊厥和抗高血压的活性。

同位素标记化合物

Cat.No: T71306

Zanamivir-13C,15N2

Cat.No: T38118

Synonym: Zanamivir-13C,15N2

Cat.No: TMID-0170

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