Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13437 |
(R,R)-Palonosetron Hydrochloride
|
Others | Others |
(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron | |||
T37246 |
Palonosetron N-oxide
|
Others | Others |
Palonosetron N-oxide is a metabolite of the serotonin (5-HT) receptor subtype 5-HT3antagonist palonosetron .1It is also a potential impurity in palonosetron preparations.2Palonosetron N-oxide is a degradation product formed by exposure to oxidative stress. 1.Stoltz, R.A., Cyong, J.-C., Shah, A., et al.Pharmacokinetic and safety evaluation of palonosetron, a 5-hydroxytryptamine-3 receptor antagonist, in U.S. and Japanese healthy subjectsJ. Clin. Pharmacol.44(5)520-531(2004) 2.Vishnu Murthy, M., S... |