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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T29924 |
Alyssin, (R)-
|
Others | Others |
Alyssin, (R)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells. | |||
T29925 |
Alyssin, (S)-
|
Others | Others |
Alyssin, (S)-, is an analogue of Sulforaphane that has been shown to have cytotoxic effect on CCRF-SB leukemia cells and lymphoblastoid cells. | |||
T26605 |
Alyssin
|
Others | Others |
Alyssin is a sulforaphane homolog and antioxidant. It induces phase II enzymes and increases Nrf2 levels in adenocarcinoma cells. It decreases the metabolism of polycyclic aromatic hydrocarbons, supressing the risk of carcinogenesis in vitro. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8281 |
(R)-Sulforaphane
L-Sulforaphane,(R)-1-异硫氰酰-4-(甲基亚磺酰)丁烷 |
Nrf2 | Immunology/Inflammation |
L-Sulforaphane 是高效的Keap1/Nrf2/ARE途径诱导剂。与 S-异构体相比,它对大鼠肝脏和肺部的致癌解毒酶系统的诱导能力更强。 | |||
TQ0207 |
Sulforaphane
萝卜硫素 |
Apoptosis; Nrf2; HDAC | Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation |
Sulforaphane 是存在于多种蔬菜中的一种天然异硫氰酸酯。它可以激活Nrf2,并通过 AMPK 依赖性信号传导抑制高糖诱导的胰腺癌。它增加肿瘤抑制蛋白的转录并抑制组蛋白脱乙酰酶的活性,具有抗癌和抗炎活性。 |