Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T39457 |
(R)-BRD3731
(R)-BRD3731 |
Others | Others |
(R)-BRD3731, a GSK3 inhibitor, specifically compound example 273. It exhibits inhibitory activity with respective IC50 values of 1.05 μM for GSK3β and 6.7 μM for GSK3α. | |||
T61578 |
BRD3731
|
Others | Others |
BRD3731 is a selective inhibitor of GSK3β, demonstrating an IC50 value of 15 nM for GSK3β and 215 nM for GSK3α. Due to its inhibitory properties, BRD3731 holds promise for investigating various medical conditions, including post-traumatic stress disorder (PTSD), psychiatric disorders, diabetes, and neurodegenerative disorders [1]. |