Powder: -20°C for 3 years | In solvent: -80°C for 1 year
λ-Cyhalothrin (Icon) 是广谱的 II 型合成除虫菊酯杀虫剂,含有 α-氰基,用于防治多种害虫。它是一种钠通道神经毒素,靶向中枢神经系统中神经元膜。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
100 mg | ¥ 310 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 310 | 现货 |
产品描述 | λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group. It is employed across various applications for controlling a wide array of pests. As a neurotoxin, λ-Cyhalothrin acts on sodium channels in neuron membranes within the central nervous system. |
体外活性 | The mechanism of λ-Cyhalothrin toxicity produces delay in sodium channel inactivation resulting in persistent depolarization of the nerve membrane. λ-Cyhalothrin produces membrane depolarization, calcium ion infl ux, and neurotransmitter release from rat brain synaptosomes[1]. λ-Cyhalothrin possesses estrogenic properties and is able to function as a xenoestrogen promoting human breast carcinoma cell proliferation in vitro[1].λ-Cyhalothrin has found multiple uses in pest (fleas, cockroaches, flies, and ants) control[1].λ-Cyhalothrin is highly effective against the malaria transmitting species of Anopheles[1]. |
体内活性 | The effect of λ-Cyhalothrin (i.p.) on memory, movement activity, and co-ordination in mice exposed to bilateral clamping of the carotid arteries (BCCA) is investigated. Neither memory nor movement co-ordination are impaired by BCCA or λ-Cyhalothrin. Exploratory locomotor activity is markedly reduced in the BCCA/LCH group. Spontaneous movement activity is significantly reduced in the BCCA/λ-Cyhalothrin group . Exposure to λ-Cyhalothrin coexisting with BCCA decreases motor activity in the mice in 2 subsequent 30-min[1]. |
别名 | lambda-Cyhalothrin, Karate, λ-氯氟氰菊酯, Icon |
分子量 | 449.85 |
分子式 | C23H19ClF3NO3 |
CAS No. | 91465-08-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (133.38 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.223 mL | 11.1148 mL | 22.2296 mL | 55.5741 mL |
5 mM | 0.4446 mL | 2.223 mL | 4.4459 mL | 11.1148 mL | |
10 mM | 0.2223 mL | 1.1115 mL | 2.223 mL | 5.5574 mL | |
20 mM | 0.1111 mL | 0.5557 mL | 1.1115 mL | 2.7787 mL | |
50 mM | 0.0445 mL | 0.2223 mL | 0.4446 mL | 1.1115 mL | |
100 mM | 0.0222 mL | 0.1111 mL | 0.2223 mL | 0.5557 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
λ-Cyhalothrin 91465-08-6 Membrane transporter/Ion channel Microbiology/Virology Sodium Channel Parasite Na channels Inhibitor λ Cyhalothrin Na+ channels inhibit lambda-Cyhalothrin depolarization λCyhalothrin Karate pesticide pyrethroid choreoatetosis acaricide Insecticide λ-氯氟氰菊酯 neurotoxin salivation Icon α-cyano inhibitor