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PTH Protein, Human, Recombinant (His)

PTH Protein, Human, Recombinant (His)

产品编号 TMPJ-00741
别名: Parathyroid hormone, Parathyrin, PTH, Parathormone

Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged with in the Golgi into secretory vesicles, the secreted into blood by exocytosis. In renal epithelium, PTH promotes conversion of Vitamin D to its active form, lowers Ca++ excretion and increases phosphate excretion. PTH also increases hematopoietic stem cell proliferation and mobilization and induces arterial vasodilation by regulating Ca++ influx in PTH1R-expressing arterial smooth muscle.

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PTH Protein, Human, Recombinant (His) Chemical Structure
PTH Protein, Human, Recombinant (His), CAS N/A
规格 价格/CNY 货期 数量
10 μg ¥ 580 5日内发货
50 μg ¥ 1,170 5日内发货
500 μg ¥ 8,300 5日内发货
1 mg ¥ 11,800 5日内发货
产品目录号及名称: PTH Protein, Human, Recombinant (His) (TMPJ-00741)
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产品描述 Parathyroid hormone (PTH) is a critical hormone in the regulation of Ca++ homeostasis. Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged with in the Golgi into secretory vesicles, the secreted into blood by exocytosis. In renal epithelium, PTH promotes conversion of Vitamin D to its active form, lowers Ca++ excretion and increases phosphate excretion. PTH also increases hematopoietic stem cell proliferation and mobilization and induces arterial vasodilation by regulating Ca++ influx in PTH1R-expressing arterial smooth muscle.
别名 Parathyroid hormone, Parathyrin, PTH, Parathormone
分子量 13 KDa (reducing condition)

存储

Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6~12 month

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Keywords

PTH Protein, Human, Recombinant (His) Parathyroid hormone Parathyrin PTH Parathormone Inhibitor inhibitor inhibit

 

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