keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI).
产品描述 | K114 binds tightly to amyloid fibrils (EC50: 20-30 nM). K114 is an efficient detector of semen-derived enhancer of virus infection (SEVI). |
体外活性 | The unusually low buffer fluorescence of K114 is due to self-quenching in sedimentable aggregates or micelles which upon interacting with amyloid fibrils undergo an enhancement in fluorescence intensity and shifts in the excitation and emission spectra [1]. |
分子量 | 393.27 |
分子式 | C22H17BrO2 |
CAS No. | 872201-12-2 |
keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (254.28 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.5428 mL | 12.7139 mL | 25.4278 mL | 63.5696 mL |
5 mM | 0.5086 mL | 2.5428 mL | 5.0856 mL | 12.7139 mL | |
10 mM | 0.2543 mL | 1.2714 mL | 2.5428 mL | 6.357 mL | |
20 mM | 0.1271 mL | 0.6357 mL | 1.2714 mL | 3.1785 mL | |
50 mM | 0.0509 mL | 0.2543 mL | 0.5086 mL | 1.2714 mL | |
100 mM | 0.0254 mL | 0.1271 mL | 0.2543 mL | 0.6357 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
K114 872201-12-2 Others K-114 K 114 Inhibitor inhibitor inhibit