Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Golotimod (SCV 07) hydrochloride 是一种免疫调节肽,具抗菌活性,能显著提升抗结核疾病研究效果。该化合物通过刺激胸腺和脾细胞增殖、改善巨噬细胞功能,展现其生物调节能力。此外,Golotimod hydrochloride 通过抑制STAT3信号传导,有效调节接受放疗或与顺铂联用治疗动物模型中的口腔粘膜炎持续时间和严重程度。还显示出对研究复发性生殖器单纯疱疹病毒 2 型 (HSV-2) 具有潜在应用价值。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
5 mg | ¥ 3,010 | 待询 | ||
10 mg | ¥ 4,710 | 待询 | ||
50 mg | ¥ 14,060 | 待询 | ||
100 mg | ¥ 19,160 | 待询 | ||
200 mg | 待询 | 待询 | ||
500 mg | 待询 | 待询 |
Golotimod hydrochloride (229305-39-9 free base) 的其他形式现货产品:
产品描述 | Golotimod hydrochloride (SCV 07 hydrochloride) is an immunomodulating peptide with antimicrobial properties. It enhances antituberculosis therapy effectiveness, promotes thymic and splenic cell proliferation, and boosts macrophage functionality. Furthermore, it inhibits STAT3 signaling, thereby modifying the duration and intensity of oral mucositis in animal models subjected to radiation or a combination of radiation and Cisplatin. Additionally, Golotimod hydrochloride has shown potential as a treatment for recurrent genital herpes simplex virus type 2 (HSV-2) [1] [2] [3]. |
体外活性 | Golotimod hydrochloride is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) [1]. Golotimod inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin [2]. |
别名 | Golotimod hydrochloride, Gamma-D-glutamyl-L-tryptophan hydrochloride, SCV 07 hydrochloride |
分子量 | 369.8 |
分子式 | C16H20ClN3O5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 125 mg/mL (338.02 mM), Sonication is recommended.
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
H2O | 1 mM | 2.7042 mL | 13.5208 mL | 27.0416 mL | 67.6041 mL |
5 mM | 0.5408 mL | 2.7042 mL | 5.4083 mL | 13.5208 mL | |
10 mM | 0.2704 mL | 1.3521 mL | 2.7042 mL | 6.7604 mL | |
20 mM | 0.1352 mL | 0.676 mL | 1.3521 mL | 3.3802 mL | |
50 mM | 0.0541 mL | 0.2704 mL | 0.5408 mL | 1.3521 mL | |
100 mM | 0.027 mL | 0.1352 mL | 0.2704 mL | 0.676 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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